pentobarbital will decrease the level or influence of solifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the extent or outcome of irinotecan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the level or influence of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the level or effect of fesoterodine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the level or influence of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.
pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can lower panobinostat concentrations by ~70% and result in therapy failure.
buprenorphine, prolonged-performing injection and pentobarbital equally raise sedation. Prevent or Use Alternate Drug. Restrict use to patients for whom different procedure choices are inadequate
Search for out knowledgeable treatment system. Quitting Nembutal use cold turkey could be risky and challenging. In some cases, barbiturate withdrawal may even lead to Loss of life.
pentobarbital will reduce the extent or result of ethotoin by affecting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Watch.
pentobarbital will increase effects of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Warning/Observe. Coadministration of ifosfamide with CYP2B6 inducers may perhaps boost metabolism of ifosfamide to its metabolite. Check for improved effects/toxicities if combined with CYP2B6 inducers.
과량일시, 펜토바르비탈은 호흡기를 억제시켜 죽음에 이르게 한다. 미국에서, 펜토바르비탈은 사형에 사용된다.
CYP3A4 inducers may perhaps boost the metabolism of clopidogrel to its Energetic metabolite. Observe individuals for likely increase in antiplatelet effects when CYP3A4 inducers are employed in combination with clopidogrel
Gather some essential information about the person overdosing if possible. It should help the health care team in the event you can offer the individual’s age, body weight, pre-existing professional medical situations, the title and energy of your drug taken, the time it here was taken, the amount taken, and if the individual was prescribed the drug or not. Never hold off the decision to understand this information if It's not readily available.
Barbiturates could potentially cause fetal injury when administered to the pregnant girl; retrospective, circumstance-managed reports have prompt a connection amongst maternal use of barbiturates and a greater-than-predicted incidence of fetal abnormalities
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